Properties of cell wall polysaccharides of raw nectarine fruits after treatment under conditions that modulate gastric digestion.

The results of the study of the physicochemical properties of the high-molecular-weight soluble and insoluble components of nectarine cell walls obtained by fruit treatment under conditions that modulate of gastric digestion are presented. Homogenized nectarine fruits were sequentially treated by natural saliva and simulated gastric fluid (SGF) at pH 1.8 and 3.0. The isolated polysaccharides were compared with polysaccharides obtained by sequential extraction of nectarine fruit with cold, hot, and acidified water, solutions of ammonium oxalate and sodium carbonate. As a result, high-molecular-weight water-soluble pectic polysaccharides, weakly bound in the cell wall, were dissolved in the simulated gastric fluid, regardless of pH. Homogalacturonan (HG) and rhamnogalacturonan-I (RG-I) were identified in all pectins. It was shown that their quantity and ability to form highly viscous solutions determine high values of the rheological characteristics of the nectarine mixture formed under simulated gastric conditions. The modifications occurring with the insoluble components under the influence of acidity of SGF were importance. They determined difference in the physicochemical properties of both the insoluble fibres and the nectarine mixtures.

[Role of health resort factors in the treatment of delayed puberty in teenage girls]. / Rol' sanatorno-kurortnykh faktorov v lechenii zaderzhki polovogo razvitiia u devochek-podrostkov.

Both treatment and effective rehabilitation play an important role in preserving the reproductive health of the girl, the future mother. Along with the search for new drug therapies for various gynecological pathologies, it is important to use physical and natural factors that are natural stimuli for the patient's body. AIM: To examine the effect of health resort factors and methods of physiotherapy on the general condition and hormonal status of girls with delayed sexual development. MATERIAL AND METHODS: 83 patients with delayed sexual development who were examined at the children's clinical sanatorium 'Zdravnitsa' in Yevpatoria (Crimea) were examined: 52 girls were included in the primary group, 31 - in the comparison group. Both groups, depending on age, were divided into subgroups: 13-14 years old and 15-17 years old. Patients in both groups received a standard treatment complex (STC). In addition to SCR, the girls of the main group were prescribed: 5% brine electrophoresis by sinusoidal modulated currents, sage and sea baths. The control group included gynecologic ally healthy adolescents: thirteen 13-14 year-old girls old in the subgroup K1 and twelve 15-17 year-old girls in the subgroup K2. Before and after treatment, all patients underwent standard clinical, gynecological, and laboratory examinations. In both groups, the dynamics of clinical and laboratory parameters, as well as gonadotropic and sex steroid hormones in the blood serum were analyzed. RESULTS: The complex of climatic and physical factors had a nonspecific general stimulating effect. There was a positive dynamics in the general condition of patients, their anthropometric indicators, hormonal status, which was more pronounced in the primary group than in the comparison group. Negative dynamics of the course of diseases in girls of both groups was not observed. CONCLUSION: The use of hardware physiotherapy and sage baths increases the effectiveness of STC. The best clinical and laboratory dynamics of the primary indices was noted in patients 13-14 years old than in patients 15-17 years old. The use of natural and preformed physical factors in treatment makes it possible to minimize the drug effect on the body and achieve the most positive treatment results with a minimum of side effects.

[Clinical case of Jeune syndrome].

The paper reports a clinical case of Jeune syndrome in a baby, in whom the diagnosis was established immediately after his birth. He was also diagnosed as having multiple congenital malformations, such as Dandy-Walker anomaly, hexadactyly of the left hand, cleft palate, choroidal colobomas in both eyes, and atrial septal defect and he also had interstitial nephritis and hepatitis.

[The actual Russian legislation in sphere of turn-over of drug agents and psychotropic substances].

The drug abuse is a social occurrence. Hence, the social economic methods are the first of all means of combating this evil. At the same time, measures of especially juridical character possess significant value since they develop corresponding legal base for applying another measures. In the Russian Federation, during fifteen years the new policy of public regulation and normative legal base in the area of legal turn-over of drug agents, psychotropic substances and their precursors were developed factually from zero ground. However, the current national legislation is not deprived of some flaws and contradictions. Frequently a uniform practice of interpretation and application of legal rules regulating the controlled turn-over is lacking. On the one hand, this circumstance decreases effectiveness of action of such rules and on the other hand favors development of situations for outflow of pharmaceuticals from legal turn-over to illegal traffic. The becoming of the Russian legislation in the area of turn-over of drug agents, precursors and psychotropic substances relates to the period of late 1990s when the Federal Law No 3 FZ "On drug agents and psychotropic substances" of January 8 1998 was developed and passed by the State Duma of the Russian Federation. The given law completely conforms to principles of legal regulation of turn-over of drug agents and psychotropic substances determined by the Constitution of the Russian Federation (provisions 76, 90, 104, 105) and federal laws ("On the government of the Russian Federation" of December 17 1997, "On the ombudsman in the Russian Federation" of February 26 1997). The main characteristic of legal rules included into given group of sources of law is that they contain regulations of general disposition as basic ones for inferior sources of law. The analysis of basic Federal law No 3 FZ "On drug agents and psychotropic substances" of January 8 1998 makes it possible to conclude that in in Russia the international legal acts are in the foundation of actual legal regulation of turn-over of drug agents and psychotropic substances.